24897-55-0

24897-55-0 structure
24897-55-0 structure
  • Name: uracil-d4
  • Chemical Name: uracil-d4
  • CAS Number: 24897-55-0
  • Molecular Formula: C4D4N2O2
  • Molecular Weight: 116.11100
  • Catalog: Research Areas Cancer
  • Create Date: 2018-02-14 08:00:00
  • Modify Date: 2024-01-06 17:51:34
  • Uracil-d4 is the deuterium labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].

Name uracil-d4
Synonyms tetradeuterio-propadiene
1,3,5,6-tetradeuterio-1H-pyrimidine-2,4-dione
Tetradeuterio-allen
tetradeuterio-allene
Tetradeuterouracil
perdeuterioallene
Perdeutero-uracil
Propadiene-d4
1,3,4,5-D4-Uracil
Description Uracil-d4 is the deuterium labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Pałasz A, et al. In search of uracil derivatives as bioactive agents. Uracils and fused uracils: Synthesis, biological activity and applications. Eur J Med Chem. 2015 Jun 5;97:582-611.  

Molecular Formula C4D4N2O2
Molecular Weight 116.11100
Exact Mass 116.05200
PSA 65.72000
Precursor  2

DownStream  1