Top Suppliers:I want be here

22855-57-8

22855-57-8 structure
22855-57-8 structure
  • Name: Brosuximide
  • Chemical Name: 3-(3-bromophenyl)pyrrolidine-2,5-dione
  • CAS Number: 22855-57-8
  • Molecular Formula: C10H8BrNO2
  • Molecular Weight: 254.08000
  • Create Date: 2018-05-30 08:00:00
  • Modify Date: 2024-02-01 18:59:57

Name 3-(3-bromophenyl)pyrrolidine-2,5-dione
Synonyms 3-(3-Bromophenyl)-2,5-pyrrolidinedione
Brosuximide
Brosuximida [INN-Spanish]
2-(m-Bromophenyl)succinimide
Imid kwasu 3-bromofenylobursztynowego [Polish]
3-Bromophenylsuccinimide
3-(3-bromophenyl)-pyrrolidine-2,5-dione
m-Bromophenylsuccinimide
Succinimide,2-(m-bromophenyl)
Brosuximidum [INN-Latin]
Density 1.606g/cm3
Boiling Point 425.7ºC at 760mmHg
Molecular Formula C10H8BrNO2
Molecular Weight 254.08000
Flash Point 211.2ºC
Exact Mass 252.97400
PSA 49.66000
LogP 1.85510
Vapour Pressure 1.88E-07mmHg at 25°C
Index of Refraction 1.601

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WN2285000
CHEMICAL NAME :
Succinimide, 2-(m-bromophenyl)-
CAS REGISTRY NUMBER :
22855-57-8
BEILSTEIN REFERENCE NO. :
1457286
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C10-H8-Br-N-O2
MOLECULAR WEIGHT :
254.10
WISWESSER LINE NOTATION :
T5VMVTJ DR CE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1750 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - ataxia
REFERENCE :
APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 40,657,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
370 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. (Warsaw, Poland) V.18-24, 1966-72. For publisher information, see PJPPAA. Volume(issue)/page/year: 23,593,1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
920 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 39,475,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
310 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 13,465,1978
HS Code 2925190090
HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%