17210-51-4

17210-51-4 structure

Name: Guvacoline Hydrobromide
Chemical Name: Guvacoline Hydrobromide
CAS Number: 17210-51-4
Molecular Formula: C₇H₁₂BrNO₂
Molecular Weight: 222.08
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2017-10-20 20:10:46
Modify Date: 2024-01-12 11:17:53
Guvacoline hydrobromide, a pyridine alkaloid found in Areca triandra, can act as a weak full agonist of atrial and ileal mAChR[1][2].

Name	Guvacoline Hydrobromide
Synonyms	methyl 1,2,3,6-tetrahydropyridine-5-carboxylate,hydrobromide

Description	Guvacoline hydrobromide, a pyridine alkaloid found in Areca triandra, can act as a weak full agonist of atrial and ileal mAChR[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> mAChR
References	[1]. Jiao Wu, et al. Tissue-specific and maturity-dependent distribution of pyridine alkaloids in Areca triandra. J Plant Res. 2019 Jul;132(4):531-540. [2]. M Wolf-Pflugmann, et al. Synthesis and muscarinic activity of a series of tertiary and quaternary N-substituted guvacine esters structurally related to arecoline and arecaidine propargyl ester. Arzneimittelforschung. 1989 May;39(5):539-44.