7616-22-0

7616-22-0 structure

Name: (±)-γ-Tocopherol
Chemical Name: 2,7,8-Trimethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol
CAS Number: 7616-22-0
Molecular Formula: C₂₈H₄₈O₂
Molecular Weight: 416.68000
Catalog: Research Areas Cancer
Create Date: 2018-12-07 16:11:02
Modify Date: 2024-01-10 13:26:45
(±)-γ-Tocopherol is an endogenous metabolite present in Blood that can be used for the research of Prostate Cancer and Endometrial Cancer[1][2][3].

Name	2,7,8-Trimethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol
Synonyms	2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol (+)-7,8-dimethyltocol 4-Pyrone 4-Pyranone 4-oxo-4H-pyran 4H-PYRAN-4-ONE

Description	(±)-γ-Tocopherol is an endogenous metabolite present in Blood that can be used for the research of Prostate Cancer and Endometrial Cancer[1][2][3].
Related Catalog	Research Areas >> Cancer
In Vitro	Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
References	[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720. [2]. Key TJ, et al. Plasma carotenoids, retinol, and tocopherols and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition study. Am J Clin Nutr. 2007 Sep;86(3):672-81. [3]. Jeong NH, et al. Preoperative levels of plasma micronutrients are related to endometrial cancer risk. Acta Obstet Gynecol Scand. 2009;88(4):434-9.

Molecular Formula	C₂₈H₄₈O₂
Molecular Weight	416.68000
Exact Mass	416.36500
PSA	29.46000
LogP	8.53180

54-28-4

7616-22-0

Literature: DSM IP Assets B.V.; SCHIEFER, Gerhard; NETSCHER, Thomas; DUCHATEAU, Alexander Lucia Leonardus Patent: WO2012/152779 A1, 2012 ; Location in patent: Page/Page column 32-33 ;

253686-88-3

526-86-3

~74%

7616-22-0

Literature: Kajiwara, M.; Sakamoto, O.; Ohta, S. Heterocycles, 1980 , vol. 14, # 12 p. 1995 - 1998

187806-29-7

7616-22-0

Literature: Rosenau, Thomas; Habicher, Wolf D. Synlett, 1997 , vol. 1997, # 2 p. 208 - 210

19849-32-2

7616-22-0

Literature: Rosenau, Thomas; Habicher, Wolf D. Synlett, 1997 , vol. 1997, # 2 p. 208 - 210

Precursor 4
54-28-4 253686-88-3 526-86-3 187806-29-7
DownStream 0

7616-22-0	96273-97-1
73980-80-0	54-28-4
187677-37-8	22373-06-4
19625-16-2	68506-86-5
104111-77-5	6991-51-1