1018332-24-5
1018332-24-5 structure
- Name: (2R,4R)-4-(((9H-FLUOREN-9-YL)METHOXY)CARBONYLAMINO)-1-(TERT-BUTOXYCARBONYL)PYRROLIDINE-2-CARBOXYLICACID
- Chemical Name: (4R)-4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-1-{[(2-methyl-2- propanyl)oxy]carbonyl}-D-proline
- CAS Number: 1018332-24-5
- Molecular Formula: C25H28N2O6
- Molecular Weight: 452.500
- Create Date: 2018-12-24 11:46:10
- Modify Date: 2024-04-03 14:54:10
| Name | (4R)-4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-1-{[(2-methyl-2- propanyl)oxy]carbonyl}-D-proline |
|---|---|
| Synonyms |
(2R-cis)-2-(Fluoromethyl)-4-hydroxy-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester
(2R,4R)-N-Boc-2-(fluoromethyl)-4-hydroxypyrrolidine (2R,4R)-1-(tert-butoxycarbonyl)-4-N-(9-fluorenylmethoxycarbonyl)aminoproline (2R,4R)-1-(tert-butoxycarbonyl)-4-hydroxypiperidine-2-carboxylic acid (4R)-4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-proline (2R,4R)-1-(tert-butoxycarbonyl)-4-hydroxy-2-(fluoromethyl)pyrrolidine 1-Pyrrolidinecarboxylicacid,2-(fluoromethyl)-4-hydroxy-,1,1-dimethylethyl ester,(2R-cis)-(9CI) 1,2-Pyrrolidinedicarboxylic acid, 4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester, (2R,4R)- (2R,4R)-tert-Butyl 2-(fluoromethyl)-4-hydroxypyrrolidine-1-carboxylate |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 650.2±55.0 °C at 760 mmHg |
| Molecular Formula | C25H28N2O6 |
| Molecular Weight | 452.500 |
| Flash Point | 347.0±31.5 °C |
| Exact Mass | 452.194733 |
| PSA | 108.66000 |
| LogP | 3.86 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.627 |
|
~%
1018332-24-5 |
| Literature: Zanardi, Franca; Burreddu, Paola; Rassu, Gloria; Auzzas, Luciana; Battistini, Lucia; Curti, Claudio; Sartori, Andrea; Nicastro, Giuseppe; Menchi, Gloria; Cini, Nicoletta; Bottonocetti, Anna; Raspanti, Silvia; Casiraghi, Giovanni Journal of Medicinal Chemistry, 2008 , vol. 51, # 6 p. 1771 - 1782 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |