17617-60-6

17617-60-6 structure

17617-60-6 structure

Name: 7-chloro-5-(2-fluorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
Chemical Name: 7-chloro-5-(2-fluorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
CAS Number: 17617-60-6
Molecular Formula: C₁₅H₁₀ClFN₂O₂
Molecular Weight: 304.70400
Create Date: 2019-01-14 08:28:33
Modify Date: 2024-02-02 18:16:00

Name	7-chloro-5-(2-fluorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
Synonyms	Ro 7-5205 3-Hydroxy-N-desalkyl-2-oxoquazepam OX 164F

Density	1.48g/cm3
Boiling Point	507.1ºC at 760mmHg
Molecular Formula	C₁₅H₁₀ClFN₂O₂
Molecular Weight	304.70400
Flash Point	260.5ºC
Exact Mass	304.04100
PSA	61.69000
LogP	2.16060
Vapour Pressure	4.18E-11mmHg at 25°C
Index of Refraction	1.668

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DF2370105

CHEMICAL NAME :: 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(o-fluorophenyl)-3-hydroxy-

CAS REGISTRY NUMBER :: 17617-60-6

BEILSTEIN REFERENCE NO. :: 0759083

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H10-Cl-F-N2-O2

MOLECULAR WEIGHT :: 304.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 774 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHMGBN Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1968- Volume(issue)/page/year: 12,74,1974

89722-88-3 structure

89722-88-3

~%

17617-60-6 structure

17617-60-6

Literature: Journal of Fluorine Chemistry, , vol. 23, p. 557 - 572