507487-89-0
507487-89-0 structure
- Name: CK7
- Chemical Name: 4-methyl-5-[2-(3-nitroanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine
- CAS Number: 507487-89-0
- Molecular Formula: C14H12N6O2S
- Molecular Weight: 328.34900
- Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
- Create Date: 2016-06-08 02:09:35
- Modify Date: 2025-08-25 11:50:28
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CK7, a Cdk2/9 inhibitor, can be used for the synthesis of Nek1 inhibitor BSc5231 and BSc5367[1].
| Name | 4-methyl-5-[2-(3-nitroanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine |
|---|---|
| Synonyms |
2wev
CK7 2c5p 1pxo Cdk2/9 Inhibitor |
| Description | CK7, a Cdk2/9 inhibitor, can be used for the synthesis of Nek1 inhibitor BSc5231 and BSc5367[1]. |
|---|---|
| Related Catalog | |
| Target |
CDK2 CDK9 |
| References |
| Molecular Formula | C14H12N6O2S |
|---|---|
| Molecular Weight | 328.34900 |
| Exact Mass | 328.07400 |
| PSA | 151.51000 |
| LogP | 3.66880 |
|
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507487-89-0 |
| Literature: Wang, Shudong; Meades, Christopher; Wood, Gavin; Osnowski, Andrew; Anderson, Sian; Yuill, Rhoda; Thomas, Mark; Mezna, Mokdad; Jackson, Wayne; Midgley, Carol; Griffiths, Gary; Fleming, Ian; Green, Simon; McNae, Iain; Wu, Su-Ying; McInnes, Campbell; Zheleva, Daniella; Walkinshaw, Malcolm D.; Fischer, Peter M. Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1662 - 1675 |
|
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507487-89-0 |
| Literature: Wang, Shudong; Midgley, Carol A.; Scaerou, Frederic; Grabarek, Joanna B.; Griffiths, Gary; Jackson, Wayne; Kontopidis, George; McClue, Steven J.; McInnes, Campbell; Meades, Christopher; Mezna, Mokdad; Plater, Andy; Stuart, Iain; Thomas, Mark P.; Wood, Gavin; Clarke, Rosemary G.; Blake, David G.; Zheleva, Daniella I.; Lane, David P.; Jackson, Robert C.; Glover, David M.; Fischer, Peter M. Journal of Medicinal Chemistry, 2010 , vol. 53, # 11 p. 4367 - 4378 |
