54665-51-9
54665-51-9 structure
- Name: Methyl acetate-PEG1-methyl acetate
- Chemical Name: methyl 2-[2-(2-methoxy-2-oxoethoxy)ethoxy]acetate
- CAS Number: 54665-51-9
- Molecular Formula: C8H14O6
- Molecular Weight: 206.19300
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-05-01 04:26:25
- Modify Date: 2024-01-07 20:42:06
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Methyl acetate-PEG1-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | methyl 2-[2-(2-methoxy-2-oxoethoxy)ethoxy]acetate |
|---|---|
| Synonyms |
dimethyl 3,6-dioxaoctane-1,8-dioate
triglycolic acid dimethyl ester methyl 2-{2-[(methoxycarbonyl)methoxy]ethoxy}acetate ethane-1,2-diyldioxy-bis-acetic acid dimethyl ester Acetic acid,2,2'-[1,2-ethanediylbis(oxy)]bis-,dimethyl ester 3,6-dioxaoctanedioic acid dimethylester |
| Description | Methyl acetate-PEG1-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C8H14O6 |
|---|---|
| Molecular Weight | 206.19300 |
| Exact Mass | 206.07900 |
| PSA | 71.06000 |
|
~%
Detail
|
| Literature: Kaulen, Johannes; Schaefer, Hans-J. Tetrahedron, 1982 , vol. 38, # 22 p. 3299 - 3308 |
| Precursor 2 | |
|---|---|
| DownStream 7 | |
![2-[16-(2-hydroxyethyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadec-7-yl]ethanol structure](https://image.chemsrc.com/caspic/411/69930-74-1.png)
