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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (R)-6-(3-Fluoro-benzyloxy)-N-(1,2,2-triMethyl-propyl)-nicotinamide
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1276013-77-4

1276013-77-4 structure

1276013-77-4 structure

Name: (R)-6-(3-Fluoro-benzyloxy)-N-(1,2,2-triMethyl-propyl)-nicotinamide
Chemical Name: (R)-N-(3,3-dimethylbutan-2-yl)-6-((3-fluorobenzyl)oxy)nicotinamide
CAS Number: 1276013-77-4
Molecular Formula: C₁₉H₂₃FN₂O₂
Molecular Weight: 330.39700
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2017-11-13 23:27:21
Modify Date: 2024-04-11 15:11:30
VU0404251 is a highly potent positive allosteric modulator of mGlu for the study of psychosis[1].

Name	(R)-N-(3,3-dimethylbutan-2-yl)-6-((3-fluorobenzyl)oxy)nicotinamide
Synonyms	(R)-6-(3-Fluoro-benzyloxy)-N-(1,2,2-trimethyl-propyl)-nicotinamide

Description	VU0404251 is a highly potent positive allosteric modulator of mGlu for the study of psychosis[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
References	[1]. Manka JT, et al. Optimization of an ether series of mGlu5 positive allosteric modulators: molecular determinants of MPEP-site interaction crossover. Bioorg Med Chem Lett. 2012 Oct 15;22(20):6481-5.

Molecular Formula	C₁₉H₂₃FN₂O₂
Molecular Weight	330.39700
Exact Mass	330.17400
PSA	51.22000
LogP	4.35500

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