944396-88-7

944396-88-7 structure

Name: NIBR-17
Chemical Name: [4,5'-Bipyrimidine]-2',6-diamine, N6-(6-methoxy-3-pyridinyl)-2-(4-morpholinyl)
CAS Number: 944396-88-7
Molecular Formula: C₁₈H₂₀N₈O₂
Molecular Weight: 380.40
Catalog: Signaling Pathways PI3K/Akt/mTOR PI3K
Create Date: 2016-02-17 16:37:12
Modify Date: 2025-08-25 20:14:12
NIBR-17 is a pan-class I PI3K inhibitor with suitable pharmacokinetic properties and inhibits tumor growth[1].

Name	[4,5'-Bipyrimidine]-2',6-diamine, N6-(6-methoxy-3-pyridinyl)-2-(4-morpholinyl)
Synonyms	5-(6-(6-methoxypyridin-3-ylamino)-2-morpholinopyrimidin-4-yl)pyrimidin-2-amine N-(6-Methoxy-3-pyridinyl)-2-(4-morpholinyl)-4,5'-bipyrimidine-2',6-diamine [4,5'-Bipyrimidine]-2',6-diamine, N-(6-methoxy-3-pyridinyl)-2-(4-morpholinyl)- NIBR-17

Description	NIBR-17 is a pan-class I PI3K inhibitor with suitable pharmacokinetic properties and inhibits tumor growth[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> PI3K
References	[1]. Burger MT, et al. Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors. ACS Med Chem Lett. 2010 Oct 13;2(1):34-8.