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70465-61-1

70465-61-1 structure
70465-61-1 structure
  • Name: N4-ETHYL-2'-DEOXYCYTIDINE
  • Chemical Name: 4-(ethylamino)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • CAS Number: 70465-61-1
  • Molecular Formula: C11H17N3O4
  • Molecular Weight: 255.27
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2016-03-23 10:04:48
  • Modify Date: 2024-01-10 17:28:14
  • N4-Ethyl-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 4-(ethylamino)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Synonyms 2'-deoxy-N4-ethyl-cytidine
Cytidine,2'-deoxy-N-ethyl
N4-Ethyldeoxycytidin
N4-ethyl-2'-deoxy-cytidine
Description N4-Ethyl-2’-deoxycytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 1.49 g/cm3
Boiling Point 466.7ºC at 760 mmHg
Molecular Formula C11H17N3O4
Molecular Weight 255.27
Flash Point 236.1ºC
Exact Mass 255.12200
PSA 96.61000

~81%

70465-61-1 structure

70465-61-1

Literature: Sergueeva, Zinaida A.; Sergueev, Dmitri S.; Shaw, Barbara Ramsay Nucleosides, Nucleotides and Nucleic Acids, 2000 , vol. 19, # 1-2 p. 275 - 282

~91%

70465-61-1 structure

70465-61-1

Literature: Kraszewski; Delort; Teoule Tetrahedron Letters, 1986 , vol. 27, # 7 p. 861 - 864

~23%

70465-61-1 structure

70465-61-1

Literature: Kraszewski; Delort; Teoule Tetrahedron Letters, 1986 , vol. 27, # 7 p. 861 - 864

~%

70465-61-1 structure

70465-61-1

Literature: Saladino, Raffaele; Mincione, Enrico; Crestini, Claudia; Mezzetti, Maurizio Tetrahedron, 1996 , vol. 52, # 19 p. 6759 - 6780