205393-22-2

205393-22-2 structure

Name: BORTEZOMIB-PINANEDIOL
Chemical Name: bortezomib-pinanediol
CAS Number: 205393-22-2
Molecular Formula: C₂₉H₃₉BN₄O₄
Molecular Weight: 518.455
Create Date: 2018-06-13 20:15:16
Modify Date: 2026-07-01 12:57:18
Bortezomib-pinanediol is a prodrug of Bortezomib, as well as a proteasome inhibitor.

Name	bortezomib-pinanediol
Synonyms	N-{(1R)-3-Methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0]dec-4-yl]butyl}-Nα-(2-pyrazinylcarbonyl)-L-phenylalaninamide 2-Pyrazinecboxamide, N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl] N-((S)-1-(((R)-3-Methyl-1-((3aS,4S,6S,7-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-cboxamide BORTEZOMIB-PINANEDIOLoxoethyl]-2-pyrazinecboxamide Bortezomib Impurity 54 (1S,2S,3R,5S)-pinanedioxy-N-pyrazinoyl-D-phenylalanyl-L-leucineboronate (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate BortezoMib VI Bortezomib pinanediol ester BortezoMib InterMediate III (BortezoMib pinanediol ester) BortezoMib interMediates N-1 Bortezomib Pinanediol Impurity N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7-Hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecboxamide Bortezomib Impurity Bortezomib intermediates III Bortezomib impurity 4/Bortezomib Pinanediol Impurity/(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate Bortezomib impurity 98 N-[(1S)-1-benzyl-2-({(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.,6~]dec-4-yl]butyl}amino)-2-oxoethyl]-2-pyrazinecboxamide (1S,2S,3R,5S)-Pinanediol N-(2-pyrazinecbony1)-L-phenylalanine-L-leucine boronate

Density	1.2±0.1 g/cm3
Boiling Point	719.5±60.0 °C at 760 mmHg
Melting Point	75-83ºC
Molecular Formula	C₂₉H₃₉BN₄O₄
Molecular Weight	518.455
Flash Point	389.0±32.9 °C
Exact Mass	518.306458
PSA	102.44000
LogP	4.81780
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.572