4546-73-0
4546-73-0 structure
- Name: 3-amino-9-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one
- Chemical Name: 5-amino-3-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2H-triazolo[4,5-d]pyrimidin-7-one
- CAS Number: 4546-73-0
- Molecular Formula: C9H12N6O4
- Molecular Weight: 268.23
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2017-08-18 13:26:50
- Modify Date: 2025-09-13 11:58:59
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8-Aza-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 5-amino-3-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2H-triazolo[4,5-d]pyrimidin-7-one |
|---|---|
| Synonyms |
5-amino-3-(2-deoxypentofuranosyl)-2,3-dihydro-7h-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
8-aza-2'-deoxy-guanosine |
| Description | 8-Aza-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 2.29g/cm3 |
|---|---|
| Boiling Point | 521.7ºC at 760 mmHg |
| Molecular Formula | C9H12N6O4 |
| Molecular Weight | 268.23 |
| Flash Point | 269.3ºC |
| Exact Mass | 268.09200 |
| PSA | 152.17000 |
| Index of Refraction | 2 |
|
~97%
4546-73-0 |
| Literature: Seela; Lampe Helvetica Chimica Acta, 1993 , vol. 76, # 6 p. 2388 - 2397 |
|
~56%
4546-73-0 |
| Literature: Seela; Lampe Helvetica Chimica Acta, 1993 , vol. 76, # 6 p. 2388 - 2397 |
|
~58%
4546-73-0 |
| Literature: Stepchenko, Vladimir A.; Seela, Frank; Esipov, Roman S.; Miroshnikov, Anatoly I.; Sokolov, Yuri A.; Mikhailopulo, Igor A. Synlett, 2012 , vol. 23, # 10 art. no. ST-2012-B0090-L, p. 1541 - 1545 |
|
~%
4546-73-0 |
| Literature: Seela; Lampe Helvetica Chimica Acta, 1993 , vol. 76, # 6 p. 2388 - 2397 |
|
~%
4546-73-0 |
| Literature: Seela; Lampe Helvetica Chimica Acta, 1993 , vol. 76, # 6 p. 2388 - 2397 |
|
~23%
4546-73-0 |
| Literature: Stepchenko, Vladimir A.; Seela, Frank; Esipov, Roman S.; Miroshnikov, Anatoly I.; Sokolov, Yuri A.; Mikhailopulo, Igor A. Synlett, 2012 , vol. 23, # 10 art. no. ST-2012-B0090-L, p. 1541 - 1545 |
| Precursor 6 | |
|---|---|
| DownStream 0 | |