60102-37-6

60102-37-6 structure
60102-37-6 structure

Name Petasitenine (neutral)
Synonyms (15R,20R)-15,20-Epoxy-15,20-dihydro-12-hydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione
Otosenin,Othosenin
Petasitenine
PETASITINENE
Density 1.29g/cm3
Boiling Point 614.7ºC at 760 mmHg
Molecular Formula C19H27NO7
Molecular Weight 381.42000
Flash Point 325.6ºC
Exact Mass 381.17900
PSA 105.67000
LogP 0.15860
Index of Refraction 1.557

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SE5085000
CHEMICAL NAME :
Petasitenine
CAS REGISTRY NUMBER :
60102-37-6
LAST UPDATED :
199510
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C19-H27-N-O7
MOLECULAR WEIGHT :
381.47

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
921 mg/kg/13W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

MUTATION DATA

TYPE OF TEST :
Unscheduled DNA synthesis
TEST SYSTEM :
Rodent - rat Liver
DOSE/DURATION :
2 umol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 45,3125,1985 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 31,207,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 31,207,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW PPTCBY Proceedings of the International Symposium of the Princess Takamatsu Cancer Research Fund. (Japan Scientific Soc. Press, 6-2-10 Hongo, Bunkyo-ku, Tokyo 113, Japan) 1st- 1971- Volume(issue)/page/year: 9,79,1979
RIDADR UN 1544
Packaging Group III
Hazard Class 6.1(b)