924854-60-4

924854-60-4 structure

Name: Tetrabenazine Metabolite
Chemical Name: 2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (2S,3R,11bR)
CAS Number: 924854-60-4
Molecular Formula: C₁₉H₂₉NO₃
Molecular Weight: 319.43800
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Monoamine Transporter
Create Date: 2017-10-24 10:06:17
Modify Date: 2026-06-30 10:44:45
Tetrabenazine Metabolite is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a high affinity (Ki=13.4 nM)[1]. Tetrabenazine Metabolite is be developed for the treatment of chorea associated with Huntington’s disease and other hyperkinetic disorders[1].

Name	2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (2S,3R,11bR)
Synonyms	(+)-β-Dihydrotetrabenazine (-)-β-Dihydrotetrabenazine (2S,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol 3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol (2S,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol (2S,3R,11bR)-Dihydrotetrabenazine (-)-β-HTBZ (-)-β-Dihydrotetrabenazine\|\|\|(-)-β-HTBZ (2S,3R,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol (+)-beta-Dihydrotetrabenazine Testosterone Impurity 33 (+)-β-(2S,3R)-DihydrotetrabenazineQ: What is (+)-β-(2S,3R)-Dihydrotetrabenazine Q: What is the CAS Number of (+)-β-(2S,3R)-Dihydrotetrabenazine Q: What is the storage condition of (+)-β-(2S,3R)-Dihydrotetrabenazine (2S,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol (2S,3R,11bR)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol (2S,3R,11bR) Tetrabenazine Related Impurity 6 Tetrabenazine Metabolite, 10 mM in DMSO

Description	Tetrabenazine Metabolite is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a high affinity (Ki=13.4 nM)[1]. Tetrabenazine Metabolite is be developed for the treatment of chorea associated with Huntington’s disease and other hyperkinetic disorders[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Monoamine Transporter
References	[1]. Yao Z, et al. Preparation and evaluation of tetrabenazine enantiomers and all eight stereoisomers of dihydrotetrabenazine as VMAT2 inhibitors. Eur J Med Chem. 2011 May;46(5):1841-8.

HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%