924854-60-4
924854-60-4 structure
- Name: Tetrabenazine Metabolite
- Chemical Name: 2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (2S,3R,11bR)
- CAS Number: 924854-60-4
- Molecular Formula: C19H29NO3
- Molecular Weight: 319.43800
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Monoamine Transporter
- Create Date: 2017-10-24 10:06:17
- Modify Date: 2024-02-10 11:22:17
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Tetrabenazine Metabolite is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a high affinity (Ki=13.4 nM)[1]. Tetrabenazine Metabolite is be developed for the treatment of chorea associated with Huntington’s disease and other hyperkinetic disorders[1].
| Name | 2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (2S,3R,11bR) |
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| Synonyms |
(2S,3R,11bR)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol
(2S,3R,11bR)-Dihydrotetrabenazine 2H-BENZO[A]QUINOLIZIN-2-OL, 1,3,4,6,7,11B-HEXAHYDRO-9,10-DIMETHOXY-3-(2-METHYLPROPYL)-, (2S,3R,11BR)- (2S,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol |
| Description | Tetrabenazine Metabolite is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a high affinity (Ki=13.4 nM)[1]. Tetrabenazine Metabolite is be developed for the treatment of chorea associated with Huntington’s disease and other hyperkinetic disorders[1]. |
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| Related Catalog | |
| References |
| Density | 1.13±0.1 g/cm3 (20 °C, 760 mmHg) |
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| Boiling Point | 457.8±45.0 °C (760 mmHg) |
| Molecular Formula | C19H29NO3 |
| Molecular Weight | 319.43800 |
| Exact Mass | 319.21500 |
| PSA | 41.93000 |
| LogP | 2.96780 |
| HS Code | 2933990090 |
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| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |