Top Suppliers:I want be here



824426-32-6

824426-32-6 structure
824426-32-6 structure
  • Name: Aeide-C1-NHS ester
  • Chemical Name: (2,5-dioxopyrrolidin-1-yl) 2-azidoacetate
  • CAS Number: 824426-32-6
  • Molecular Formula: C6H6N4O4
  • Molecular Weight: 198.13600
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-06-23 19:16:15
  • Modify Date: 2024-01-03 15:21:06
  • Aeide-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name (2,5-dioxopyrrolidin-1-yl) 2-azidoacetate
Synonyms 2,5-Pyrrolidinedione,1-[(azidoacetyl)oxy]
Description Aeide-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C6H6N4O4
Molecular Weight 198.13600
Exact Mass 198.03900
PSA 113.43000
Storage condition 2-8°C