35536-53-9

35536-53-9 structure

Name: 11-deoxy Prostaglandin E2
Chemical Name: 7-[(1R,2R)-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
CAS Number: 35536-53-9
Molecular Formula: C₂₀H₃₂O₄
Molecular Weight: 336.47
Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
Create Date: 2016-06-14 15:12:54
Modify Date: 2024-01-14 20:15:03
11-Deoxy Prostaglandin E2 is a selective agonist of EP4 with an EC50 of 0.66 nM. 11-Deoxy Prostaglandin E2 is an analog of prostaglandin E2. 11-Deoxy Prostaglandin E2 can be used in study bone healing, heart failure, and other receptor associated conditions[1][2].

Name	7-[(1R,2R)-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
Synonyms	11-Deoxy-PGE2 (5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,13-dien-1-oic acid Prosta-5,13-dien-1-oic acid, 15-hydroxy-9-oxo-, (5Z,13E,15S)-

Description	11-Deoxy Prostaglandin E2 is a selective agonist of EP4 with an EC50 of 0.66 nM. 11-Deoxy Prostaglandin E2 is an analog of prostaglandin E2. 11-Deoxy Prostaglandin E2 can be used in study bone healing, heart failure, and other receptor associated conditions[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
References	[1]. Holt MC, et al. Improved homology modeling of the human & rat EP4 prostanoid receptors. BMC Mol Cell Biol. 2019 Aug 27;20(1):37. [2]. Ungrin MD, et al. Key structural features of prostaglandin E(2) and prostanoid analogs involved in binding and activation of the human EP(1) prostanoid receptor. Mol Pharmacol. 2001 Jun;59(6):1446-56.