945633-30-7

945633-30-7 structure

Name: (+)-Biotin-PEG2-azide
Chemical Name: 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-(2-azidoethoxy)ethoxy]ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)
CAS Number: 945633-30-7
Molecular Formula: C₁₆H₂₈N₆O₄S
Molecular Weight: 400.49600
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-03-08 06:15:28
Modify Date: 2025-08-25 21:16:06
Biotin-PEG2-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-(2-azidoethoxy)ethoxy]ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)
Synonyms	(+)-Biotin-PEG3-CH2CH2N3 (+)-Biotin-PEG3-azide (+)-Biotin-PEG3-CH2CH2azide

Description	Biotin-PEG2-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.