5132-79-6

5132-79-6 structure

Name: Guanosine,2'-deoxy-1-methyl-
Chemical Name: n1-methyl-2'-deoxyguanosine
CAS Number: 5132-79-6
Molecular Formula: C₁₁H₁₅N₅O₄
Molecular Weight: 281.27
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-12-13 10:24:07
Modify Date: 2024-01-03 11:58:48
2’-Deoxy-N1-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	n1-methyl-2'-deoxyguanosine
Synonyms	2'-deoxy-1-methylguanosine 2-Amino-3-methyl-3H-imidazole-4-carboxylic acid ethyl ester 1-N-methyl-2-amino imidazole-5-carboxylic acid ethyl ester 1-methyl-2'-deoxy-guanosine 2-Amino-5-carbethoxy-1-methyl-imidazol 1-Methyl-2-amino-5-carbethoxyimidazol ethyl 2-amino-1-methyl-1H-imidazole-5-carboxylate 1-N-methyl-2'-deoxyguanosine 1-methyldeoxyguanosine

Description	2’-Deoxy-N1-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.