84625-59-2

84625-59-2 structure

84625-59-2 structure

Name: 1-benzhydryl-4-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]piperazine
Chemical Name: 1-benzhydryl-4-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]piperazine
CAS Number: 84625-59-2
Molecular Formula: C₂₉H₃₄N₂O₂
Molecular Weight: 442.59200
Create Date: 2018-03-18 08:00:00
Modify Date: 2024-01-11 00:26:25

Name	1-benzhydryl-4-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]piperazine
Synonyms	DOTARIZINE Dotarizinum Dotarizina

Density	1.122 g/cm3
Boiling Point	557.4ºC at 760 mmHg
Melting Point	100-101ºC
Molecular Formula	C₂₉H₃₄N₂O₂
Molecular Weight	442.59200
Flash Point	147.9ºC
Exact Mass	442.26200
PSA	24.94000
LogP	4.94940
Index of Refraction	1.587

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TL6610000

CHEMICAL NAME :: Piperazine, 1-(diphenylmethyl)-4-(3-(2-phenyl-1,3-dioxolan-2-yl)p ropyl)-

CAS REGISTRY NUMBER :: 84625-59-2

LAST UPDATED :: 199106

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C29-H34-N2-O2

MOLECULAR WEIGHT :: 442.65

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >8 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1103,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 42500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1103,1987

HS Code	2933599090

3308-98-3 structure

3308-98-3

841-77-0 structure

841-77-0

~53%

84625-59-2 structure

84625-59-2

Literature: Gubert; Braso; Sacristan; Ortiz Arzneimittel-Forschung/Drug Research, 1987 , vol. 37, # 10 p. 1103 - 1107

90-99-3 structure

90-99-3

~%

84625-59-2 structure

84625-59-2

Literature: Arzneimittel-Forschung/Drug Research, , vol. 37, # 10 p. 1103 - 1107

Precursor 3
3308-98-3 841-77-0 90-99-3
DownStream 0

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%