Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Talinolol
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

57460-41-0

57460-41-0 structure
57460-41-0 structure
  • Name: rac Talinolol
  • Chemical Name: rac-Talinolol
  • CAS Number: 57460-41-0
  • Molecular Formula: C20H33N3O3
  • Molecular Weight: 363.494
  • Create Date: 2018-05-18 08:00:00
  • Modify Date: 2024-01-16 10:40:24
  • Talinolol is a beta(1)-adrenergic receptor antagonist and a probe drug for P-glycoprotein (P-gp) activity in humans.

Name rac-Talinolol
Synonyms 1-Cyclohexyl-3-(4-{2-hydroxy-3-[(2-methyl-2-propanyl)amino]propoxy}phenyl)urea
1-{4-[3-(tert-Butylamino)-2-hydroxypropoxy]phenyl}-3-cyclohexylurea
Talinolol
Urea, N-cyclohexyl-N'-[4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-
1-[4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl]-3-cyclohexylurea
Density 1.1±0.1 g/cm3
Boiling Point 520.0±50.0 °C at 760 mmHg
Melting Point 160-162ºC
Molecular Formula C20H33N3O3
Molecular Weight 363.494
Flash Point 268.3±30.1 °C
Exact Mass 363.252197
PSA 82.62000
LogP 3.20
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.552

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YS7594200
CHEMICAL NAME :
Urea, N-cyclohexyl-N'-(4-(3-((1,1-dimethylethyl)amino)-2-hy droxypropoxy)phenyl)-, (+-)-
CAS REGISTRY NUMBER :
57460-41-0
LAST UPDATED :
199706
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H33-N3-O3
MOLECULAR WEIGHT :
363.56

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 38,409,1983
HS Code 2924299090

~%

57460-41-0 structure

57460-41-0

Literature: Eckardt; Carstens; Fiedler Pharmazie, 1975 , vol. 30, # 10 p. 633 - 637

~%

57460-41-0 structure

57460-41-0

Literature: Eckardt; Carstens; Fiedler Pharmazie, 1975 , vol. 30, # 10 p. 633 - 637

~%

57460-41-0 structure

57460-41-0

Literature: Eckardt; Carstens; Fiedler Pharmazie, 1975 , vol. 30, # 10 p. 633 - 637
Precursor  4

DownStream  0

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%