Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Ciproquazone
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Purity: 98.0%
Stocking Period: Inquiry
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33453-23-5

33453-23-5 structure

33453-23-5 structure

Name: Ciproquazone
Chemical Name: 1-(cyclopropylmethyl)-6-methoxy-4-phenylquinazolin-2-one
CAS Number: 33453-23-5
Molecular Formula: C₁₉H₁₈N₂O₂
Molecular Weight: 306.35800
Create Date: 2018-07-08 13:22:38
Modify Date: 2024-01-14 17:44:14
Ciproquazone has analgesic activity and is used to treat spondylitis.

Name	1-(cyclopropylmethyl)-6-methoxy-4-phenylquinazolin-2-one
Synonyms	1-Cyclopropylmethyl-4-phenyl-6-methoxy-2(1H)-chinazolinon 1-Cyclopropylmethyl-4-phenyl-6-methoxy-2(1H)-quinazolinone 1-cyclopropylmethyl-6-methoxy-4-phenyl-1H-quinazolin-2-one Ciproquazonum [INN-Latin] CIPROQUAZONE SL-573 Ciproquazona 1-(Cyclopropyl-methyl)-4-phenyl-6-methoxy-1H-chinazolinon-(2) 2(1H)-Quinazolinone,1-(cyclopropylmethyl)-6-methoxy-4-phenyl 1-(Cyclopropylmethyl)-6-methoxy-4-phenyl-2(1H)-quinazolinone Ciproquazona [INN-Spanish]

Description	Ciproquazone has analgesic activity and is used to treat spondylitis.
References	1. Vega S, et al. Thiophene isosteres: synthesis and biological evaluation of 3-substituted derivatives of 4-phenyl-2-thioxo-benzo [4, 5] thieno [2, 3-d] pyrimidine. European journal of medicinal chemistry, 1991, 26(3): 323-329.

Density	1.26g/cm3
Boiling Point	483.8ºC at 760mmHg
Molecular Formula	C₁₉H₁₈N₂O₂
Molecular Weight	306.35800
Flash Point	246.4ºC
Exact Mass	306.13700
PSA	44.12000
LogP	3.48210
Index of Refraction	1.653

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA3100333

CHEMICAL NAME :: 2(1H)-Quinazolinone, 1-(cyclopropylmethyl)-6-methoxy-4-phenyl-

CAS REGISTRY NUMBER :: 33453-23-5

BEILSTEIN REFERENCE NO. :: 0761592

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C19-H18-N2-O2

MOLECULAR WEIGHT :: 306.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 gm/kg/30D-I

TOXIC EFFECTS :: Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in testicular weight

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 13,1991,1979

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9100 mg/kg/13W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 13,1991,1979

95-50-1 structure

95-50-1

36942-71-9 structure

36942-71-9

~%

33453-23-5 structure

33453-23-5

Literature: Sumitomo Chemical Company, Limited Patent: US4387223 A1, 1983 ;

Precursor 2
95-50-1 36942-71-9
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