Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: CZC8004
Price: ￥13096.0/5g ￥1396.0/250mg ￥3506.0/1g ￥876.0/100mg
Purity: 95.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Dianilinopyrimidine_01
Price: $750.0/100mg $1500.0/250mg $3000.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N2-(4-(AMINOMETHYL)PHENYL)-5-FLUORO-N4-PHENYLPYRIMIDINE-2,4-DIAMINE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

916603-07-1

916603-07-1 structure

916603-07-1 structure

Name: CZC8004
Chemical Name: N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine
CAS Number: 916603-07-1
Molecular Formula: C₁₇H₁₆FN₅
Molecular Weight: 309.341
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Bcr-Abl
Create Date: 2018-12-29 18:22:03
Modify Date: 2024-01-10 00:03:14
CZC-8004 is a pan-kinase inhibitor and binds a range of tyrosine kinases, including ABL kinase.

Name	N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine
Synonyms	N-[4-(Aminomethyl)phenyl]-5-fluoro-N-phenyl-2,4-pyrimidinediamine CZC8004 2-N-[4-(aminomethyl)phenyl]-5-fluoro-4-N-phenylpyrimidine-2,4-diamine 2,4-Pyrimidinediamine, N-[4-(aminomethyl)phenyl]-5-fluoro-N-phenyl-

Description	CZC-8004 is a pan-kinase inhibitor and binds a range of tyrosine kinases, including ABL kinase.
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl Research Areas >> Cancer
References	[1]. CZC-8004 is a pan-kinase inhibitor, with low micromolar IC₅₀ values for tyrosine kinase. [2]. Bantscheff M, et al. Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors. Nat Biotechnol. 2007 Sep;25(9):1035-44.

Density	1.3±0.1 g/cm3
Boiling Point	514.1±60.0 °C at 760 mmHg
Molecular Formula	C₁₇H₁₆FN₅
Molecular Weight	309.341
Flash Point	264.7±32.9 °C
Exact Mass	309.138977
PSA	75.86000
LogP	2.27
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.699

HS Code	2921499090

916603-12-8 structure

916603-12-8

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916603-07-1 structure

916603-07-1

Literature: US2009/238808 A1, ;

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%