Shanghai Nianxing Industrial Co., Ltd
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N2-(4-(AMINOMETHYL)PHENYL)-5-FLUORO-N4-PHENYLPYRIMIDINE-2,4-DIAMINE
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Purity: 98.0%
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916603-07-1

916603-07-1 structure

916603-07-1 structure

Name: CZC8004
Chemical Name: N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine
CAS Number: 916603-07-1
Molecular Formula: C₁₇H₁₆FN₅
Molecular Weight: 309.341
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Bcr-Abl
Create Date: 2018-12-29 18:22:03
Modify Date: 2026-07-01 14:45:51
CZC-8004 is a pan-kinase inhibitor and binds a range of tyrosine kinases, including ABL kinase.

Name	N2-(4-(Aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine
Synonyms	N2-(4-(aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4 N-[4-(Aminomethyl)phenyl]-5-fluoro-N-phenyl-2,4-pyrimidinediamine N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenyl-2,4-pyrimidinediamine Tget-5 (Kinase Probe Tool, APM-1)/Dianilinopyrimidine_01 DianilinopyriMidine_01 2-n-[4-(aminomethyl)phenyl]-5-fluoro-4-n-phenylpyrimidine-2,4-diamine 2-N-[4-(aminomethyl)phenyl]-5-fluoro-4-N-phenylpyrimidine-2,4-diamine N-(4-broMophenyl)-N-(naphthalen-2-yl) Dianilinopyrimidine_01(CZC8004) N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenylpyrimidine-2,4-diamine CZC-8004, 10 mM in DMSO CZC-8004 N-(4-broMophenyl)-N-(naphthalen-2-yl) naphthalen-1-aMine CZC 8004,HER1,Vascul endothelial owth factor rector,ErbB-1,idermal owth factor rector,CZC-8004,CZC8004,aminopyrimidine,Inhibitor,tyrosine kinases,CZC 00008004,EGFR,CZC00008004,inhibit,VEGFR 2,4-Pyrimidinediamine, N2-[4-(aminomethyl)phenyl]-5-fluoro-N4-phenyl

Description	CZC-8004 is a pan-kinase inhibitor and binds a range of tyrosine kinases, including ABL kinase.
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl Research Areas >> Cancer
References	[1]. CZC-8004 is a pan-kinase inhibitor, with low micromolar IC₅₀ values for tyrosine kinase. [2]. Bantscheff M, et al. Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors. Nat Biotechnol. 2007 Sep;25(9):1035-44.

Density	1.3±0.1 g/cm3
Boiling Point	514.1±60.0 °C at 760 mmHg
Molecular Formula	C₁₇H₁₆FN₅
Molecular Weight	309.341
Flash Point	264.7±32.9 °C
Exact Mass	309.138977
PSA	75.86000
LogP	2.27
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.699

HS Code	2921499090

916603-12-8 structure

916603-12-8

~%

916603-07-1 structure

916603-07-1

Literature: US2009/238808 A1, ;

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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