Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-(3-AZASPIRO(5.5)UNDEC-3-YL)-4′-FLUORO-BUTYROPHENONE HYDROCHLORIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

64-60-8

64-60-8 structure

64-60-8 structure

Name: 4-(3-AZASPIRO(5.5)UNDEC-3-YL)-4′-FLUORO-BUTYROPHENONE HYDROCHLORIDE
Chemical Name: 4-(3-azaspiro[5.5]undecan-3-yl)-1-(4-fluorophenyl)butan-1-one,hydrochloride
CAS Number: 64-60-8
Molecular Formula: C₂₀H₂₉ClFNO
Molecular Weight: 353.90200
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyrimidine compound Methoxypyrimidine
Create Date: 2016-03-20 06:44:06
Modify Date: 2024-01-10 11:14:40

Name	4-(3-azaspiro[5.5]undecan-3-yl)-1-(4-fluorophenyl)butan-1-one,hydrochloride

Boiling Point	449.6ºC at 760 mmHg
Molecular Formula	C₂₀H₂₉ClFNO
Molecular Weight	353.90200
Flash Point	225.7ºC
Exact Mass	353.19200
PSA	20.31000
LogP	5.57480

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EU1139350

CHEMICAL NAME :: Butyrophenone, 4-(3-azaspiro(5.5)undec-3-yl)-4'-fluoro-, hydrochloride

CAS REGISTRY NUMBER :: 64-60-8

LAST UPDATED :: 198910

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H28-F-N-O.Cl-H

MOLECULAR WEIGHT :: 353.95

WISWESSER LINE NOTATION :: T6N DXTJ A3VR DF& D-& AL6XTJ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,62,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Behavioral - analgesia

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,62,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,62,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 45 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Behavioral - analgesia

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,62,1965