Name | (+)-Cloprostenol isopropyl ester |
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Synonyms |
Cloprostenol isopropyl ester
CPG 6112-95 |
Description | Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of (+)-Cloprostenol (HY-107381). Cloprostenol isopropyl ester is a FP receptor agonist with a Ki value of 28 nM[1][2]. |
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Related Catalog | |
In Vivo | Cloprostenol isopropyl ester (25 μg/kg; i.p.; daily, for 4 weeks; male mice) induces changes in the evolution of the spermatogenesis and spermiogenesis[1]. Cloprostenol isopropyl ester (1 μg, 30 μL; injected into the eye; for 2, 4 and 6 h) causes pupil constriction in the cat. Cloprostenol isopropyl ester has an efficacious ocular hypotensive in the lasered monkey[2]. Animal Model: Male mice (50–80 days)[1] Dosage: 25 μg/kg Administration: Intraperitoneal injection; daily, for 4 weeks Result: Stimulated the androgen synthesis in a time-dependent manner. |
References |
Density | 1.227±0.06 g/cm3 |
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Molecular Formula | C25H35ClO6 |
Molecular Weight | 466.99500 |
Exact Mass | 466.21200 |
PSA | 96.22000 |
LogP | 4.06200 |
Water Solubility | Insuluble (4.1E-3 g/L) (25 ºC) |