73971-82-1
73971-82-1 structure
- Name: 1-[(2R,4R,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione
- Chemical Name: 3'-Azido-2',3'-dideoxy-3,4-dihydrothymidine
- CAS Number: 73971-82-1
- Molecular Formula: C10H13N5O4
- Molecular Weight: 267.24
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2017-08-30 14:49:01
- Modify Date: 2026-07-30 11:54:57
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3-epi-Azido-3-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 3'-Azido-2',3'-dideoxy-3,4-dihydrothymidine |
|---|---|
| Synonyms |
1-(3-Azido-2,3-dideoxy-beta-D-threo-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
3'-azido-3'-deoxythymidine AZT(threo), AzddXyloT 3'-beta-Azido-3'-deoxy thyMidine 3’-beta-Azido-3’-deoxy thymidine AZT(threo), HIV-1 rlication inhibitor, Zidovudine’s related substance Zidovudine Impurity 14 1-(3-beta-Azido-2,3-dideoxy-beta-D-threopenta-furanosyl)thyMine 3’-β-Azido-3’-deoxy thymidine 3'-i-Azido-3'-deoxythyMidine Zidovudine Impurity 4 5'OHCH2alloAZT |
| Description | 3-epi-Azido-3-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C10H13N5O4 |
|---|---|
| Molecular Weight | 267.24 |
| Exact Mass | 267.09700 |
| PSA | 134.33000 |
|
~83%
73971-82-1 |
| Literature: Dong, Guimin; Zhang, Liangren; Zhang, Lihe Helvetica Chimica Acta, 2003 , vol. 86, # 10 p. 3516 - 3524 |
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~%
73971-82-1 |
| Literature: Dong, Guimin; Zhang, Liangren; Zhang, Lihe Helvetica Chimica Acta, 2003 , vol. 86, # 10 p. 3516 - 3524 |
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~%
73971-82-1 |
| Literature: Wengel; Pedersen Synthesis, 1991 , # 6 p. 451 - 454 |
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~%
73971-82-1 |
| Literature: Gauthier, Christine; Ramondenc, Yvan; Ple, Gerard Tetrahedron, 2001 , vol. 57, # 35 p. 7513 - 7517 |
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~%
73971-82-1 |
| Literature: Gauthier, Christine; Ramondenc, Yvan; Ple, Gerard Tetrahedron, 2001 , vol. 57, # 35 p. 7513 - 7517 |
|
~%
73971-82-1 |
| Literature: Wengel; Pedersen Synthesis, 1991 , # 6 p. 451 - 454 |
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73971-82-1 |
| Literature: Sun, Jingbo; Liu, Xinyu; Li, Hongming; Duan, Ronghui; Wu, Jinchang Helvetica Chimica Acta, 2012 , vol. 95, # 5 p. 772 - 779 |
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~%
73971-82-1 |
| Literature: Wengel; Pedersen Synthesis, 1991 , # 6 p. 451 - 454 |
| Precursor 6 | |
|---|---|
| DownStream 0 | |