987-02-0

987-02-0 structure

Name: Demecycline
Chemical Name: (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
CAS Number: 987-02-0
Molecular Formula: C₂₁H₂₂N₂O₈
Molecular Weight: 430.40800
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-06-29 17:25:03
Modify Date: 2025-08-20 16:24:03
Demecycline is the C6-demethylated derivative of Tetracycline (HY-A0107) against bacterial infections including pneumonia and other respiratory tract infections[1].

Name	(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
Synonyms	A IX Demecycline Demethyltetracycline Demecyclinum Demeciclina Demecycline (USAN/INN) 6-Demethyltetracyclin

Description	Demecycline is the C6-demethylated derivative of Tetracycline (HY-A0107) against bacterial infections including pneumonia and other respiratory tract infections[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Yang W, Kong L, Wang Q, Deng Z, You D. Metabolic engineering of a methyltransferase for production of drug precursors demecycline and demeclocycline in Streptomyces aureofaciens. Synth Syst Biotechnol. 2020;5(3):121-130. Published 2020 Jun 23. [2]. Results from the Swedish national screening programme 2005.