118292-36-7
118292-36-7 structure
- Name: Pyrindamycin A
- Chemical Name: methyl (2R,8S)-8-(chloromethyl)-4-hydroxy-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carboxylate
- CAS Number: 118292-36-7
- Molecular Formula: C26H26ClN3O8
- Molecular Weight: 543.95300
- Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
- Create Date: 2017-09-07 15:10:15
- Modify Date: 2024-01-04 14:47:35
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Pyrindamycin A is an antibiotic that inhibits DNA synthesis. Pyrindamycin A shows antitumor activities against murine leukemia, exhibits stronger cytotoxic activities towards murine and human tumor cell lines and especially towards doxorubicin-resistant cells, inhibits P388 and P388/ADR cells with the same IC50 of 3.9 μg/ml[1].
| Name | methyl (2R,8S)-8-(chloromethyl)-4-hydroxy-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-7,8-dihydro-3H-pyrrolo[3,2-e]indole-2-carboxylate |
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| Synonyms |
duocarmycin C2
Pyrindamycin A |
| Description | Pyrindamycin A is an antibiotic that inhibits DNA synthesis. Pyrindamycin A shows antitumor activities against murine leukemia, exhibits stronger cytotoxic activities towards murine and human tumor cell lines and especially towards doxorubicin-resistant cells, inhibits P388 and P388/ADR cells with the same IC50 of 3.9 μg/ml[1]. |
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| Related Catalog | |
| References |
| Density | 1.433g/cm3 |
|---|---|
| Boiling Point | 767ºC at 760mmHg |
| Molecular Formula | C26H26ClN3O8 |
| Molecular Weight | 543.95300 |
| Flash Point | 417.7ºC |
| Exact Mass | 543.14100 |
| PSA | 139.42000 |
| LogP | 3.62500 |
| Vapour Pressure | 2.28E-24mmHg at 25°C |
| Index of Refraction | 1.643 |