132172-61-3
132172-61-3 structure
- Name: DOTAP chloride
- Chemical Name: 2,3-di(octadec-9-enoyloxy)propyl-trimethylazanium
- CAS Number: 132172-61-3
- Molecular Formula: C42H80ClNO4
- Molecular Weight: 663.08900
- Catalog: Research Areas Others
- Create Date: 2018-12-18 23:18:58
- Modify Date: 2025-08-25 19:34:35
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DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1].
| Name | 2,3-di(octadec-9-enoyloxy)propyl-trimethylazanium |
|---|---|
| Synonyms |
2,3-dioleyloxypropyltrimethylammonium chloride
1,2-dioleoyl-3-trimethylammonium-propane chloride 1,2-dioleoyl-3-trimethylammonium-propane chloride salt DOTAP chloride |
| Description | DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: Cationic Lipid[1] |
| In Vitro | liposomes are reorganized by associating with DNA. The transfection efficiency of DOTAP liposomes is mainly influenced by lipid composition and cell type, but not by size or zeta potential[1]. |
| References |
| Melting Point | 35-38ºC |
|---|---|
| Molecular Formula | C42H80ClNO4 |
| Molecular Weight | 663.08900 |
| Exact Mass | 662.60900 |
| PSA | 52.60000 |
| LogP | 12.22260 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |