143032-85-3

143032-85-3 structure

Name: 1alpha-Hydroxy VD4
Chemical Name: (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5S)-5,6-dimethylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
CAS Number: 143032-85-3
Molecular Formula: C₂₈H₄₆O₂
Molecular Weight: 414.66400
Catalog: Signaling Pathways Vitamin D Related VD/VDR
Create Date: 2017-04-01 10:37:47
Modify Date: 2026-07-01 17:32:53
1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells. IC50 value；Target: VD analog

Name	(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5S)-5,6-dimethylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
Synonyms	9,10-Secoergosta-5,7,10-triene-1,3-diol, (1α,3β,5Z,7E)- (9CI) (1R,3S,Z)-5-(2-((1R,3aS,7,E)-1-((2R,5S)-5,6-dimethylhtan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-dio 1alpha-Hydroxyvitamin D4 1 ALPHA-HYDROXY VITAMIN D4;1Α-HYDROXY VITAMIN D4 1α-Hydroxy vitaMin D4 Doxercalciferol impurity 4/Dihydro-Doxercalciferol Doxercalciferol Impurity 12 (1R,3S,Z)-5-((E)-2-((7-1-((2R,5S)-5,6-Dimethylhtan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol (1R,3S,Z)-5-(2-((1R,3aS,7,E)-1-((2R,5S)-5,6-Dimethylhtan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 1α-Hydroxyvitamin D4 Doxercalciferol Impurity 4 (1alpha,3beta,5Z,7E)-9,10-Secoergosta-5,7,10-triene-1,3-diol (1R,3S,Z)-5-((E)-2-((1R,3aS,7-1-((2R,5S)-5,6-Dimethylhtan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol 1α-Hydroxy VD4 CS-0805

Description	1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells. IC50 value；Target: VD analog
Related Catalog	Signaling Pathways >> Vitamin D Related >> VD/VDR Research Areas >> Cancer
References	[1]. M Makishima, et al. Growth inhibition and differentiation induction in human monoblastic leukaemia cells by 1alpha-hydroxyvitamin D derivatives and their enhancement by combination with hydroxyurea. British Journal of Cancer (1998) 77, 33-39