21888-98-2

21888-98-2 structure

Name: benzetimide
Chemical Name: benzetimide
CAS Number: 21888-98-2
Molecular Formula: C₂₃H₂₆N₂O₂
Molecular Weight: 398.92600
Catalog: API Nervous system medication Cholinergic
Create Date: 2018-09-29 15:38:34
Modify Date: 2024-01-10 18:24:56
Dexetimide ((+)-Benzetimide) is a high-affinity muscarinic receptor antagonist and a potent and persistent anticholinergic agent used to treat neuroleptic-induced parkinsonism[1].

Name	benzetimide
Synonyms	Dexbenzetimide DEXETIMIDE HCL Dexbenzetimid Dextrobenzetimide

Description	Dexetimide ((+)-Benzetimide) is a high-affinity muscarinic receptor antagonist and a potent and persistent anticholinergic agent used to treat neuroleptic-induced parkinsonism[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> mAChR
References	[1]. Speck AL, et al. The absolute configuration and crystal structure of the anticholinergic drug dexbenzetimide. Nature. 1971 Aug 20;232(5312):575-6. [2]. Müller-Gärtner HW, et al. Imaging muscarinic cholinergic receptors in human brain in vivo with Spect, [123I]4-iododexetimide, and [123I]4-iodolevetimide. J Cereb Blood Flow Metab. 1992 Jul;12(4):562-70.