6812-36-8

6812-36-8 structure
6812-36-8 structure
  • Name: HO-PEG16-OH
  • Chemical Name: 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
  • CAS Number: 6812-36-8
  • Molecular Formula: C32H66O17
  • Molecular Weight: 722.85600
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-08-19 14:43:44
  • Modify Date: 2025-08-25 09:51:33
  • HO-PEG16-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonyms hexadecaethylene glycol
EINECS 229-886-9
3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-Pentadecaoxaheptatetracontane-1,47-diol
Description HO-PEG16-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.116g/cm3
Boiling Point 714.7ºC at 760 mmHg
Molecular Formula C32H66O17
Molecular Weight 722.85600
Flash Point 386.1ºC
Exact Mass 722.43000
PSA 178.91000
Index of Refraction 1.466
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