DC Chemicals Limited
China
Product Name: SU5208
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

62540-08-3

62540-08-3 structure

62540-08-3 structure

Name: SU5208
Chemical Name: 3-(thiophen-2-ylmethylidene)-1H-indol-2-one
CAS Number: 62540-08-3
Molecular Formula: C₁₃H₉NOS
Molecular Weight: 227.28200
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK VEGFR
Create Date: 2017-07-05 02:11:04
Modify Date: 2024-01-17 15:34:25
SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2)[1].

Name	3-(thiophen-2-ylmethylidene)-1H-indol-2-one
Synonyms	MFCD01444960

Description	SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	VEGFR2
References	[1]. Camila Muñoz, et al. Study of differences in the VEGFR2 inhibitory activities between semaxanib and SU5205 using 3D-QSAR, docking, and molecular dynamics simulations. J Mol Graph Model. 2012 Feb;32:39-48.

Molecular Formula	C₁₃H₉NOS
Molecular Weight	227.28200
Exact Mass	227.04000
PSA	57.34000
LogP	3.37880
Storage condition	2-8°C

98-03-3 structure

98-03-3

59-48-3 structure

59-48-3

~%

62540-08-3 structure

62540-08-3

Literature: Mokrosz, Maria J.; Charakchieva-Minol, Sijka; Koziol, Aneta; Klodzinska, Aleksandra; Chojnacka-Wojcik, Ewa Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 9 p. 1229 - 1231

Precursor 2
98-03-3 59-48-3
DownStream 0