57944-13-5

57944-13-5 structure

Name: 3'-Deoxy-3'-fluorouridine
Chemical Name: 1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
CAS Number: 57944-13-5
Molecular Formula: C₉H₁₁FN₂O₅
Molecular Weight: 246.19
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-06-28 05:34:18
Modify Date: 2024-01-08 19:35:12
3′-Deoxy-3′-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Synonyms	1-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)uracil 3'-Deoxy-3'-fluorouridine 3'-Fluoro-3'-deoxyuridine Uridine,3'-deoxy-3'-fluoro Uridine, 3'-deoxy-3'-fluoro-

Description	3′-Deoxy-3′-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.