- DC Chemicals Limited
- China
- Product Name: Proctolin
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Taiwan Oyi peptide Co. Ltd
- China
- Product Name: ARG--TYR--LEU--PRO-THR
- Price: $Inquiry/1mg $Inquiry/100kg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Vinnie
57966-42-4
57966-42-4 structure
- Name: Proctolin
- Chemical Name: 2-[[1-[2-[[2-[[2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoic acid
- CAS Number: 57966-42-4
- Molecular Formula: C30H48N8O8
- Molecular Weight: 648.75100
- Catalog: Peptides
- Create Date: 2016-04-22 10:20:10
- Modify Date: 2024-01-10 09:48:02
-
Proctolin is an endogenous pentapeptide that acts as an excitatory neuromodulator.
| Name | 2-[[1-[2-[[2-[[2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoic acid |
|---|---|
| Synonyms |
Arg-tyr-leu-pro-thr
Proctolin |
| Description | Proctolin is an endogenous pentapeptide that acts as an excitatory neuromodulator. |
|---|---|
| Related Catalog | |
| In Vitro | Proctolin can increase the frequency of action potentials, increase the amplitude of muscle contraction, and initiate activity in quiescent systems[1]. In the arthropods, Proctolin acts as a neuromodulator and possibly as a neurohormone. It does not appear to function as a conventional neurotransmitter[2]. Proctolin is a pentapeptide with the mature peptide of RYLPT, and it is the first insect neuropeptide to be sequenced and chemically characterized. The first identification of a Proctolin precursor gene is CG7105 in D. melanogaster. Although a previous study showed that Proctolin is absent in B. mori, this pentapeptide is recently identified in a proteomic analysis of B. mori wings. However, the Bombyx Proctolin gene does not produce a mature peptide because cleavage sites are not present at the N-terminal and C-terminal of the RYLPT sequence, and a similar gene is observed in C. suppressalis. Therefore, a true Proctolin has been considered to be not observed in B. mori and C. suppressalis[3]. |
| References |
[2]. Orchard I, et al. Proctolin: a review with emphasis on insects. J Neurobiol. 1989 Jul;20(5):470-96. |
| Molecular Formula | C30H48N8O8 |
|---|---|
| Molecular Weight | 648.75100 |
| Exact Mass | 648.36000 |
| PSA | 283.76000 |
| LogP | 2.83220 |
| Storage condition | 2-8℃ |