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581065-94-3

581065-94-3 structure
581065-94-3 structure
  • Name: Tos-PEG5-Boc
  • Chemical Name: 16-(p-toluenesulfonyl)-4,7,10,13,16-pentaoxahexadecanoic acid tert-butyl ester
  • CAS Number: 581065-94-3
  • Molecular Formula: C22H36O9S
  • Molecular Weight: 476.58100
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-09-01 15:29:52
  • Modify Date: 2024-01-14 10:27:25
  • Tos-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 16-(p-toluenesulfonyl)-4,7,10,13,16-pentaoxahexadecanoic acid tert-butyl ester
Synonyms MFCD22574810
Description Tos-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

Molecular Formula C22H36O9S
Molecular Weight 476.58100
Exact Mass 476.20800
PSA 114.97000
LogP 3.57930
Precursor  0

DownStream  2