72944-19-5

72944-19-5 structure

Name: Artepillin C
Chemical Name: (E)-3-[4-hydroxy-3,5-bis(3-methylbut-2-enyl)phenyl]prop-2-enoic acid
CAS Number: 72944-19-5
Molecular Formula: C₁₉H₂₄O₃
Molecular Weight: 300.39
Catalog: Research Areas Cancer
Create Date: 2018-05-26 08:00:00
Modify Date: 2024-01-03 22:43:29
Artepillin C has gastroprotective, anti-inflammatory, antimicrobial, antioxidant, antitumor and choleretic activity. Artepillin C can be isolated from Brazilian green propolis[1][2].

Name	(E)-3-[4-hydroxy-3,5-bis(3-methylbut-2-enyl)phenyl]prop-2-enoic acid
Synonyms	3-[4-hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl]-2(E)-propenoic acid 3-{4-hydroxy-3,5-di-(3-methyl-2-butenyl)phenyl}-2(E)-propenoic acid Artepillin C 3-[4-hydroxy-3,5-bis-(3-methyl-2-butenyl)phenyl]-2-propenic acid artepillin 3-[4-hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl]-2-propenoic acid (E)-3-{4-hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl}-2-propenoic acid

Description	Artepillin C has gastroprotective, anti-inflammatory, antimicrobial, antioxidant, antitumor and choleretic activity. Artepillin C can be isolated from Brazilian green propolis[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Kobal MB,et al. Correlating Artepillin C cytotoxic activity on HEp-2 cells with bioinspired systems of plasma membranes. Mater Sci Eng C Mater Biol Appl. 2020 Jul;112:110943. [2]. Beserra FP, et al. Artepillin C as an outstanding phenolic compound of Brazilian green propolis for disease treatment: A review on pharmacological aspects. Phytother Res. 2020 Sep 15.

Density	1.092g/cm3
Boiling Point	447.672ºC at 760 mmHg
Molecular Formula	C₁₉H₂₄O₃
Molecular Weight	300.39
Flash Point	238.674ºC
Exact Mass	300.17300
PSA	57.53000
LogP	4.50740
Index of Refraction	1.586

72944-04-8

~80%

72944-19-5

Literature: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Patent: EP1184362 A1, 2002 ; Location in patent: Page column 16 ;

1208233-12-8

~71%

72944-19-5

Literature: Tani, Hiroko; Hasumi, Keiko; Tatefuji, Tomoki; Hashimoto, Ken; Koshino, Hiroyuki; Takahashi, Shunya Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 1 p. 151 - 157

540-38-5

72944-19-5

Literature: Uto, Yoshihiro; Hirata, Akihiko; Fujita, Tomoya; Takubo, Syunsuke; Nagasawa, Hideko; Hori, Hitoshi Journal of Organic Chemistry, 2002 , vol. 67, # 7 p. 2355 - 2357

870-63-3

72944-19-5

Literature: Uto, Yoshihiro; Hirata, Akihiko; Fujita, Tomoya; Takubo, Syunsuke; Nagasawa, Hideko; Hori, Hitoshi Journal of Organic Chemistry, 2002 , vol. 67, # 7 p. 2355 - 2357

107390-44-3

72944-19-5

Literature: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Patent: EP1184362 A1, 2002 ; Location in patent: Page column 18 ;

Precursor 5
72944-04-8 1208233-12-8 540-38-5 870-63-3
107390-44-3
DownStream 0

72944-19-5	78835-00-4
72944-04-8	107259-50-7
874124-48-8	117176-19-9
67244-49-9	82262-97-3
105650-12-2	4694-58-0