113146-74-0

113146-74-0 structure

Name: Physalin L
Chemical Name: (1S,2S,3R,5R,6S,7R,14R,15S,18R,21S,22R,25S)-5,7,18-Trihydroxy-1,14,21,25-tetramethyl-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,10-diene-13,19,24,27-tetrone
CAS Number: 113146-74-0
Molecular Formula: C₂₈H₃₂O₁₀
Molecular Weight: 528.548
Catalog: Signaling Pathways Immunology/Inflammation NO Synthase
Create Date: 2018-06-30 16:53:22
Modify Date: 2025-08-26 01:04:57
Physalin L inhibits LPS-induced NO production in macrophages with the average inhibitory rate of 70.97%. Anti-inflammatory activity[1].

Name	(1S,2S,3R,5R,6S,7R,14R,15S,18R,21S,22R,25S)-5,7,18-Trihydroxy-1,14,21,25-tetramethyl-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,10-diene-13,19,24,27-tetrone
Synonyms	1,17:2,6-Dimethano-8H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,19(1H,10H)-tetrone, 2,3,6,6a,8a,9,10a,10b,12,16,16a,17-dodecahydro-8a,16,17-trihydroxy-2,3,6a,10b-tetramethyl-, (1R,2S,3S,6R,6aS,8aS,10aS,10bR,16R,16aS,17R,18aR)- (1S,2R,3R,5R,6S,7R,14R,15S,18S,21S,22R,25S)-5,7,18-Trihydroxy-1,14,21,25-tetramethyl-4,20,23-trioxaheptacyclo[20.3.1.1.0.0.0.0]heptacosa-8,10-diene-13,19,24,27-tetrone

Description	Physalin L inhibits LPS-induced NO production in macrophages with the average inhibitory rate of 70.97%. Anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NO Synthase
References	[1]. Long Ji, et al. Physalins with anti-inflammatory activity are present in Physalis alkekengi var. franchetii and can function as Michael reaction acceptors. Steroids. 2012 Apr;77(5):441-7.