537034-15-4

537034-15-4 structure

Name: N-(2-Aminophenyl)-N'-phenylheptanediamide
Chemical Name: N'-(2-aminophenyl)-N-phenylheptanediamide
CAS Number: 537034-15-4
Molecular Formula: C₁₉H₂₃N₃O₂
Molecular Weight: 325.40500
Catalog: Research Areas Cancer
Create Date: 2018-06-13 16:04:51
Modify Date: 2024-01-02 20:08:52
NKL 22 is a HDAC inhibitor. The value of IC 50 is 78 uM NKL 22 increase frataxin protein concentrationsNKL 22 inhibitors increase FXN mRNA in FRDA lymphocytes.HDAC inhibitors act directly on FXN. [1]

Name	N'-(2-aminophenyl)-N-phenylheptanediamide
Synonyms	IN1468 Histone Deacetylase Inhibitor IV NKL 22 N-(2-Aminophenyl)-N'-phenylheptanediamide HDAC inhibitor IV

Description	NKL 22 is a HDAC inhibitor. The value of IC 50 is 78 uM NKL 22 increase frataxin protein concentrationsNKL 22 inhibitors increase FXN mRNA in FRDA lymphocytes.HDAC inhibitors act directly on FXN. [1]
Related Catalog	Research Areas >> Cancer
Target	HDAC:78 μM (IC50, in HeLa nuclear)
References	[1]. D Herman et al. Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia. Nat Chem Biol, 2006 Oct, 2(10):551-8.