332941-25-0
332941-25-0 structure
- Name: Amino-PEG7-amine
- Chemical Name: O,O′-Bis(2-aminoethyl)hexaethylene Glycol
- CAS Number: 332941-25-0
- Molecular Formula: C16H36N2O7
- Molecular Weight: 368.46600
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-06-17 18:36:08
- Modify Date: 2024-01-04 12:03:19
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Amino-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | O,O′-Bis(2-aminoethyl)hexaethylene Glycol |
|---|---|
| Synonyms | 2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine |
| Description | Amino-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C16H36N2O7 |
|---|---|
| Molecular Weight | 368.46600 |
| Exact Mass | 368.25200 |
| PSA | 116.65000 |
| LogP | 0.42060 |
| Storage condition | 2-8°C |
|
~%
332941-25-0 |
| Literature: Reynolds, Bambi; Miller, Rachel; Williams, John G.; Anderson, Jon P. Nucleosides, Nucleotides and Nucleic Acids, 2008 , vol. 27, # 1 p. 18 - 30 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |