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332941-25-0

332941-25-0 structure
332941-25-0 structure
  • Name: Amino-PEG7-amine
  • Chemical Name: O,O′-Bis(2-aminoethyl)hexaethylene Glycol
  • CAS Number: 332941-25-0
  • Molecular Formula: C16H36N2O7
  • Molecular Weight: 368.46600
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-06-17 18:36:08
  • Modify Date: 2024-01-04 12:03:19
  • Amino-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name O,O′-Bis(2-aminoethyl)hexaethylene Glycol
Synonyms 2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Description Amino-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H36N2O7
Molecular Weight 368.46600
Exact Mass 368.25200
PSA 116.65000
LogP 0.42060
Storage condition 2-8°C
Precursor  1

DownStream  0