109882-25-9
- Name: Methyl 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2- yl}butanoate
- Chemical Name: Methyl 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2- yl}butanoate
- CAS Number: 109882-25-9
- Molecular Formula: C17H23Cl2N3O2
- Molecular Weight: 372.28900
- Create Date: 2018-12-27 14:19:25
- Modify Date: 2026-07-07 11:08:49
| Name | Methyl 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2- yl}butanoate |
|---|---|
| Synonyms |
bendamustine methyl ester
methyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl Bendamustine Related Impurity Celecoxib metabolite M3 Methyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1h-benzo[d]imidazol-2-yl)butanoate PRIMARY ALCOHOL METABOLITE OF CELECOXIB 1H-Benzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1-methyl-, methyl ester Hydroxy Celecoxib Bendamustine Related Impurity 20 5-[Bis(2-chloroethyl)amino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Methyl Ester Methylhydroxy-Celecoxib 4'-Hydroxycelecoxib Bendamustine impurity 24/Bendamustine Methyl Ester/5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Methyl Ester Bendamustine Impurity 32 Bendamustine Impurity 66 |
| Molecular Formula | C17H23Cl2N3O2 |
|---|---|
| Molecular Weight | 372.28900 |
| Exact Mass | 371.11700 |
| PSA | 47.36000 |
| LogP | 3.35300 |
|
~99%
109882-25-9 |
| Literature: CEPHALON, INC.; CHEN, Jian; PRZYUSKI, Katrin; ROEMMELE, Renee, Caroline Patent: WO2010/42568 A1, 2010 ; Location in patent: Page/Page column 19-20 ; |
|
~91%
109882-25-9 |
| Literature: CEPHALON, INC.; BAKALE, Roger, P.; BROWN, Peter, D.; CHEN, Jian; DRAGER, Anthony, S.; LABELL, Rachel, Y.; MCKEAN, Robert, E.; PATEL, Piyush, R.; ROEMMELE, Renee, C. Patent: WO2014/75035 A1, 2014 ; Location in patent: Page/Page column 15 ; |
|
~%
109882-25-9 |
| Literature: Arevipharma GmbH; Schickaneder, Helmut; Schickaneder, Christian; Limmert, Michael Patent: US2013/184471 A1, 2013 ; Location in patent: Paragraph 0146; 0147; 0148; 0149; 0150 ; |
|
~%
109882-25-9 |
| Literature: Chen, Jian; Przyuski, Katrin; Roemmele, Renee; Bakale, Roger P. Organic Process Research and Development, 2011 , vol. 15, # 5 p. 1063 - 1072 |
|
~%
109882-25-9 |
| Literature: Chen, Jian; Przyuski, Katrin; Roemmele, Renee; Bakale, Roger P. Organic Process Research and Development, 2011 , vol. 15, # 5 p. 1063 - 1072 |
|
~%
109882-25-9 |
| Literature: Chen, Jian; Przyuski, Katrin; Roemmele, Renee; Bakale, Roger P. Organic Process Research and Development, 2011 , vol. 15, # 5 p. 1063 - 1072 |
|
~%
109882-25-9 |
| Literature: Chen, Jian; Przyuski, Katrin; Roemmele, Renee; Bakale, Roger P. Organic Process Research and Development, 2011 , vol. 15, # 5 p. 1063 - 1072 |
|
~%
109882-25-9 |
| Literature: Werner; Letsch; Ihn Pharmazie, 1987 , vol. 42, # 4 p. 272 - 273 |
|
~%
109882-25-9 |
| Literature: Werner; Letsch; Ihn Pharmazie, 1987 , vol. 42, # 4 p. 272 - 273 |
| Precursor 10 | |
|---|---|
| DownStream 1 | |