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2062-84-2

2062-84-2 structure

2062-84-2 structure

Name: Benperidol
Chemical Name: Benperidol
CAS Number: 2062-84-2
Molecular Formula: C₂₂H₂₄FN₃O₂
Molecular Weight: 381.44
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2018-06-19 02:52:07
Modify Date: 2026-07-02 18:29:26
Benperidol is a relatively old antipsychotic drug. Benperidol is a butyrophenone antipsychotic, with the highest neuroleptic potency in terms of D2 receptor blockade[1].

Name	Benperidol
Synonyms	1-(1-(3-(p-fluorobenzoyl)propyl)-4-piperidyl)-2-benzimidazolinone R 4584 Benperidol CRS 1-[1-[3-(p-fluorobenzoyl)propyl]-4-piperidyl]-2-benzimidazolinone 8089 C. B Benperidol, 10 mM in DMSO 8089c.b 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one 1-{1-[4-(4-Fluorophenyl)-4-oxobutyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one Frenactil Mcn-jr-4584 2h-benzimidazol-2-one,1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidinyl)-1 Benzoperidol Glianimon R4584; ANQUIL; R 4584; R-4584; FRENACTIL; FRENACTYL; GLIANIMON 1-{1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one 1-[1-[4-(p-Fluorophenyl)-4-oxobutyl]piperidin-4-yl]-2-benzimidazolinone glianimonmite 2H-Benzimidazol-2-one, 1-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1,3-dihydro 3-[1-[4-(4-fluorophenyl)-4-keto-butyl]-4-piperidyl]-1H-benzimidazol-2-one 1-(1-(3-(p-fluorobenzoyl)propyl)-4-piperidyl)-2-benzimidazolinon 1-[1-[4-(4-FLUOROPHENYL)-4-OXOBUTYL]PIPERIDIN-4-YL]-1H-BENZO[D]IMIDAZOL-2(3H)-ONE 3-[1-[4-(4-Fluorophenyl)-4-oxobutyl]piperidin-4-yl]-1H-benzimidazol-2-one EINECS 218-172-2 3-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1H-benzimidazol-2-one Benzeridol 1-(1-(3-(4-fluorobenzoyl)propyl)-4-piperidyl)benzimidazol-2-one r4584 MFCD00866672 2-Benzimidazolinone, 1-[1-[3-(p-fluorobenzoyl)propyl]-4-piperidyl] Glianimon mite 1-(4-Fluorophenyl)-4-[4-(2-hydroxy-1H-benzimidazol-1-yl)-1-piperidinyl]-1-butanone Benzperidol 1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-piperidyl]-1,3-dihydro-2H-benzimidazol-2-one (3-(p-Fluorobenzoyl)propyl)-4-piperidyl-2-benzimidazolinone Anquil Phenoperidol Frenactyl 1-{1-[4-(4-Fluorophenyl)-4-oxobutyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one 8089c.b. Concilium

Description	Benperidol is a relatively old antipsychotic drug. Benperidol is a butyrophenone antipsychotic, with the highest neuroleptic potency in terms of D2 receptor blockade[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Leucht S, et al. Benperidol for schizophrenia. Cochrane Database Syst Rev. 2005;2005(2):CD003083.

Density	1.2±0.1 g/cm3
Molecular Formula	C₂₂H₂₄FN₃O₂
Molecular Weight	381.44
Exact Mass	381.185242
PSA	58.10000
LogP	4.09
Vapour Pressure	7.96E-17mmHg at 25°C
Index of Refraction	1.595

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DE1900000

CHEMICAL NAME :: 2-Benzimidazolinone, 1-(1-(3-(p-fluorobenzoyl)propyl)-4-piperidyl)-

CAS REGISTRY NUMBER :: 2062-84-2

BEILSTEIN REFERENCE NO. :: 0900981

LAST UPDATED :: 199612

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C22-H24-F-N3-O2

MOLECULAR WEIGHT :: 381.49

WISWESSER LINE NOTATION :: T56 BNVNJ B- DT6NTJ A3VR DF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 220 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Autonomic Nervous System - central sympatholytic Behavioral - alteration of classical conditioning

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 21 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 432 mg/kg

TOXIC EFFECTS :: Behavioral - ataxia Behavioral - rigidity (including catalepsy) Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - rigidity (including catalepsy)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 204 mg/kg

TOXIC EFFECTS :: Behavioral - ataxia Behavioral - rigidity (including catalepsy) Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 192 umol/kg

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 5,231,1984

13530-68-2 structure

13530-68-2

34104-74-0 structure

34104-74-0

~%

2062-84-2 structure

2062-84-2

Literature: US3936468 A1, ;

Precursor 2
13530-68-2 34104-74-0
DownStream 0

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