83546-42-3

83546-42-3 structure

Name: 2'-Fluoro-5-ethylarabinosyluracil
Chemical Name: 5-ethyl-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
CAS Number: 83546-42-3
Molecular Formula: C₁₁H₁₅FN₂O₅
Molecular Weight: 274.25
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-12-26 18:27:56
Modify Date: 2024-01-09 00:09:17
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

Name	5-ethyl-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Synonyms	1-[5-(2-Fluoroethyl)-D-arabinopyranosyl]-2,4(1H,3H)-pyrimidinedione FEAU 1-Dfafeu 1-(2-Deoxy-2-fluoroarabinofuranosyl)-5-ethyluracil 1-[(3S,4R,5S)-6-(2-Fluoroethyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]-2,4(1H,3H)-pyrimidinedione 2,4(1H,3H)-Pyrimidinedione, 1-[(5ξ)-6,7-dideoxy-7-fluoro-D-arabino-heptopyranosyl]- 1-[(5ξ)-6,7-Dideoxy-7-fluoro-D-arabino-heptopyranosyl]-2,4(1H,3H)-pyrimidinedione 2'-Fluoro-5-ethylarabinosyluracil 1-[(5ξ)-6,7-Dideoxy-7-fluoro-D-arabino-heptopyranosyl]pyrimidine-2,4(1H,3H)-dione

Description	1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.