2441-41-0

2441-41-0 structure

Name: PALGLY
Chemical Name: 2-(hexadecanoylamino)acetic acid
CAS Number: 2441-41-0
Molecular Formula: C₁₈H₃₅NO₃
Molecular Weight: 313.48
Catalog: Biochemical Amino acids and their derivatives Glycine derivatives
Create Date: 2018-08-08 18:22:57
Modify Date: 2025-08-28 07:42:37
Palmitoylglycine, a novel endogenous lipid, acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Palmitoylglycine induces transient influx of calcium followed by nitric oxide production via calcium-sensitive nitric-oxide synthase enzymes. Palmitoylglycine potently inhibits heat-evoked firing of nociceptive neurons in rat dorsal horn[1].

Name	2-(hexadecanoylamino)acetic acid
Synonyms	N-Ethanoyl-Hexadecanamide PALGLY N-hexadecanoyl glycine Palmitoylglycine QV1MV15 N-palmitatoylglycyne N-(1-Oxohexadecyl)glycine N-Hexadecanoylglycine Glycine, N-(1-oxohexadecyl)- Hexadecanoylaminoacetic acid N-palmitoyl glycine Hexadecanoylaminoacetic acid,N-palmitoyl glycine 2-(Hexadecanoylamino)acetic acid N-palmitoyl glycine N-Palmitoylglycine

Description	Palmitoylglycine, a novel endogenous lipid, acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Palmitoylglycine induces transient influx of calcium followed by nitric oxide production via calcium-sensitive nitric-oxide synthase enzymes. Palmitoylglycine potently inhibits heat-evoked firing of nociceptive neurons in rat dorsal horn[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Neurological Disease
References	[1]. Neta Rimmerman, et al. N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Mol Pharmacol. 2008 Jul;74(1):213-24.

Personal Protective Equipment	Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
RIDADR	NONH for all modes of transport
HS Code	2924199090

14464-31-4

56-40-6

~76%

2441-41-0

Literature: McIlhinney; Harvey Journal of Mass Spectrometry, 1995 , vol. 30, # 6 p. 900 - 910

57-10-3

56-40-6

2441-41-0

214706-34-0

2441-41-0

56-40-6

112-67-4

2441-41-0

Literature: Bondi; Frankl Biochemische Zeitschrift, 1909 , vol. 17, p. 552

544-31-0

111-57-9

142-78-9

142-58-5

7112-02-9

Detail

Literature: Conopco, Inc., d/b/a UNILEVER Patent: US2007/299269 A1, 2007 ; Location in patent: Page/Page column 5-6; 7 ;

6000-44-8

112-67-4

2441-41-0

Literature: Iyer, Venkataraman N.; Sheth, Geeta N.; Subrahmanyam, V. V. R. Journal of the Indian Chemical Society, 1982 , vol. 59, # 7 p. 856 - 859

112-67-4

2441-41-0

Literature: KYUSHU UNIVERSITY; NISSAN CHEMICAL INDUSTRIES, LTD. Patent: US2012/35108 A1, 2012 ;

57-10-3

2441-41-0

59660-78-5

2441-41-0

Literature: Abderhalden; Funk Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1910 , vol. 65, p. 66

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%