1357160-72-5
1357160-72-5 structure
- Name: URB 937
- Chemical Name: urb937
- CAS Number: 1357160-72-5
- Molecular Formula: C20H22N2O4
- Molecular Weight: 354.400
- Create Date: 2016-11-06 21:33:52
- Modify Date: 2024-01-07 19:29:25
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URB937 is a potent fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 26.8 nM, in vitro) that does not penetrate the blood-brain barrier, thus preventing arachidonoyl ethanolamidedeactivation only in peripheral tissues.
| Name | urb937 |
|---|---|
| Synonyms |
cyclohexylcarbamic acid 3'-carbamoyl-6-hydroxybiphenyl-3-yl ester
3'-Carbamoyl-6-hydroxy-3-biphenylyl cyclohexylcarbamate Cyclohexylcarbaldehyddiallylacetal Carbamic acid, N-cyclohexyl-, 3'-(aminocarbonyl)-6-hydroxy[1,1'-biphenyl]-3-yl ester |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 562.8±50.0 °C at 760 mmHg |
| Molecular Formula | C20H22N2O4 |
| Molecular Weight | 354.400 |
| Flash Point | 294.2±30.1 °C |
| Exact Mass | 354.157959 |
| PSA | 101.65000 |
| LogP | 2.38 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.639 |
| RIDADR | NONH for all modes of transport |
|---|
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~93%
1357160-72-5 |
| Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; UNIVERSITA DEGLI STUDI DI URBINO "CARLO BO"; UNIVERSITA DEGLI STUDI DI PARMA; PIOMELLI, Daniele; CLAPPER, Jason, R.; MORENO-SANZ, Guillermo; DURANTI, Andrea; TONTINI, Andrea; MOR, Marco; TARZIA, Giorgio Patent: WO2012/15704 A2, 2012 ; Location in patent: Page/Page column 27 ; WO 2012/015704 A2 |
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1357160-72-5 |
| Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; UNIVERSITA DEGLI STUDI DI URBINO "CARLO BO"; UNIVERSITA DEGLI STUDI DI PARMA; PIOMELLI, Daniele; CLAPPER, Jason, R.; MORENO-SANZ, Guillermo; DURANTI, Andrea; TONTINI, Andrea; MOR, Marco; TARZIA, Giorgio Patent: WO2012/15704 A2, 2012 ; WO 2012/015704 A2 |
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1357160-72-5 |
| Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; UNIVERSITA DEGLI STUDI DI URBINO "CARLO BO"; UNIVERSITA DEGLI STUDI DI PARMA; PIOMELLI, Daniele; CLAPPER, Jason, R.; MORENO-SANZ, Guillermo; DURANTI, Andrea; TONTINI, Andrea; MOR, Marco; TARZIA, Giorgio Patent: WO2012/15704 A2, 2012 ; WO 2012/015704 A2 |
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1357160-72-5 |
| Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; UNIVERSITA DEGLI STUDI DI URBINO "CARLO BO"; UNIVERSITA DEGLI STUDI DI PARMA; PIOMELLI, Daniele; CLAPPER, Jason, R.; MORENO-SANZ, Guillermo; DURANTI, Andrea; TONTINI, Andrea; MOR, Marco; TARZIA, Giorgio Patent: WO2012/15704 A2, 2012 ; WO 2012/015704 A2 |
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1357160-72-5 |
| Literature: Fiorelli, Claudio; Scarpelli, Rita; Piomelli, Daniele; Bandiera, Tiziano Organic Process Research and Development, 2013 , vol. 17, # 3 p. 359 - 367 |
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~%
1357160-72-5 |
| Literature: Fiorelli, Claudio; Scarpelli, Rita; Piomelli, Daniele; Bandiera, Tiziano Organic Process Research and Development, 2013 , vol. 17, # 3 p. 359 - 367 |
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~%
1357160-72-5 |
| Literature: Fiorelli, Claudio; Scarpelli, Rita; Piomelli, Daniele; Bandiera, Tiziano Organic Process Research and Development, 2013 , vol. 17, # 3 p. 359 - 367 |
| Precursor 5 | |
|---|---|
| DownStream 0 | |