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1357160-72-5

1357160-72-5 structure
1357160-72-5 structure
  • Name: URB 937
  • Chemical Name: urb937
  • CAS Number: 1357160-72-5
  • Molecular Formula: C20H22N2O4
  • Molecular Weight: 354.400
  • Create Date: 2016-11-06 21:33:52
  • Modify Date: 2025-08-23 16:23:42
  • URB937 is a potent fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 26.8 nM, in vitro) that does not penetrate the blood-brain barrier, thus preventing arachidonoyl ethanolamidedeactivation only in peripheral tissues.

Name urb937
Synonyms cyclohexylcarbamic acid 3'-carbamoyl-6-hydroxybiphenyl-3-yl ester
3'-Carbamoyl-6-hydroxy-3-biphenylyl cyclohexylcarbamate
Cyclohexylcarbaldehyddiallylacetal
Carbamic acid, N-cyclohexyl-, 3'-(aminocarbonyl)-6-hydroxy[1,1'-biphenyl]-3-yl ester
Density 1.3±0.1 g/cm3
Boiling Point 562.8±50.0 °C at 760 mmHg
Molecular Formula C20H22N2O4
Molecular Weight 354.400
Flash Point 294.2±30.1 °C
Exact Mass 354.157959
PSA 101.65000
LogP 2.38
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.639
RIDADR NONH for all modes of transport

~93%

1357160-72-5 structure

1357160-72-5

Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; UNIVERSITA DEGLI STUDI DI URBINO "CARLO BO"; UNIVERSITA DEGLI STUDI DI PARMA; PIOMELLI, Daniele; CLAPPER, Jason, R.; MORENO-SANZ, Guillermo; DURANTI, Andrea; TONTINI, Andrea; MOR, Marco; TARZIA, Giorgio Patent: WO2012/15704 A2, 2012 ; Location in patent: Page/Page column 27 ; WO 2012/015704 A2

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1357160-72-5 structure

1357160-72-5

Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; UNIVERSITA DEGLI STUDI DI URBINO "CARLO BO"; UNIVERSITA DEGLI STUDI DI PARMA; PIOMELLI, Daniele; CLAPPER, Jason, R.; MORENO-SANZ, Guillermo; DURANTI, Andrea; TONTINI, Andrea; MOR, Marco; TARZIA, Giorgio Patent: WO2012/15704 A2, 2012 ; WO 2012/015704 A2

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1357160-72-5 structure

1357160-72-5

Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; UNIVERSITA DEGLI STUDI DI URBINO "CARLO BO"; UNIVERSITA DEGLI STUDI DI PARMA; PIOMELLI, Daniele; CLAPPER, Jason, R.; MORENO-SANZ, Guillermo; DURANTI, Andrea; TONTINI, Andrea; MOR, Marco; TARZIA, Giorgio Patent: WO2012/15704 A2, 2012 ; WO 2012/015704 A2

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1357160-72-5 structure

1357160-72-5

Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; UNIVERSITA DEGLI STUDI DI URBINO "CARLO BO"; UNIVERSITA DEGLI STUDI DI PARMA; PIOMELLI, Daniele; CLAPPER, Jason, R.; MORENO-SANZ, Guillermo; DURANTI, Andrea; TONTINI, Andrea; MOR, Marco; TARZIA, Giorgio Patent: WO2012/15704 A2, 2012 ; WO 2012/015704 A2

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1357160-72-5 structure

1357160-72-5

Literature: Fiorelli, Claudio; Scarpelli, Rita; Piomelli, Daniele; Bandiera, Tiziano Organic Process Research and Development, 2013 , vol. 17, # 3 p. 359 - 367

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1357160-72-5 structure

1357160-72-5

Literature: Fiorelli, Claudio; Scarpelli, Rita; Piomelli, Daniele; Bandiera, Tiziano Organic Process Research and Development, 2013 , vol. 17, # 3 p. 359 - 367

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1357160-72-5 structure

1357160-72-5

Literature: Fiorelli, Claudio; Scarpelli, Rita; Piomelli, Daniele; Bandiera, Tiziano Organic Process Research and Development, 2013 , vol. 17, # 3 p. 359 - 367
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