119458-27-4

119458-27-4 structure
119458-27-4 structure
  • Name: 5-Ethyl-5-phenylimidazolidine-2,4-dione-d5
  • Chemical Name: 5-ethyl-5-(2,3,4,5,6-pentadeuteriophenyl)imidazolidine-2,4-dione
  • CAS Number: 119458-27-4
  • Molecular Formula: C11H7D5N2O2
  • Molecular Weight: 209.26
  • Create Date: 2016-01-22 21:16:44
  • Modify Date: 2024-01-13 18:21:38
  • 5-Ethyl-5-phenylimidazolidine-2,4-dione-d5 is deuterium labeled 5-Ethyl-5-phenylimidazolidine-2,4-dione.

Name 5-ethyl-5-(2,3,4,5,6-pentadeuteriophenyl)imidazolidine-2,4-dione
Synonyms Desmethylmephenytoin-d5
Normephenytoin-d5
Ethylphenylhydantoin-d5
Nirvanol-d5
Description 5-Ethyl-5-phenylimidazolidine-2,4-dione-d5 is deuterium labeled 5-Ethyl-5-phenylimidazolidine-2,4-dione.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Melting Point 186-189ºC
Molecular Formula C11H7D5N2O2
Molecular Weight 209.26
Exact Mass 209.12100
PSA 58.20000
LogP 1.78890
Index of Refraction 1.539