158747-02-5
158747-02-5 structure
- Name: Frovatriptan
- Chemical Name: (6R)-6-(methylamino)-6,7,8,9-tetrahydro-5H-carbazole-3-carboxamide
- CAS Number: 158747-02-5
- Molecular Formula: C14H17N3O
- Molecular Weight: 243.30
- Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
- Create Date: 2017-08-31 10:36:16
- Modify Date: 2024-01-17 10:30:35
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Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura[1].
| Name | (6R)-6-(methylamino)-6,7,8,9-tetrahydro-5H-carbazole-3-carboxamide |
|---|---|
| Synonyms |
Frovatriptan (INN)
Auradol Frova Frovelan Miguard Rilamig UNII-H82Q2D5WA7 Migard Allegro |
| Description | Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Stefan Evers, et al. Efficacy of frovatriptan as compared to other triptans in migraine with aura. |
| Density | 1.27g/cm3 |
|---|---|
| Boiling Point | 515.2ºC at 760mmHg |
| Molecular Formula | C14H17N3O |
| Molecular Weight | 243.30 |
| Flash Point | 265.4ºC |
| Exact Mass | 243.13700 |
| PSA | 71.90000 |
| LogP | 2.61860 |
| Vapour Pressure | 1.01E-10mmHg at 25°C |
| Index of Refraction | 1.667 |