121524-18-3

121524-18-3 structure

121524-18-3 structure

Name: (E)-1-[(2R)-2-(2-hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one
Chemical Name: (E)-1-[(2R)-2-(2-hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one
CAS Number: 121524-18-3
Molecular Formula: C₂₃H₂₅N₃O₂
Molecular Weight: 375.46400
Create Date: 2016-07-19 20:28:21
Modify Date: 2024-02-01 12:31:27

Name	(E)-1-[(2R)-2-(2-hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one
Synonyms	2-Piperidineethanol,1-(1-oxo-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-2-propenyl)-,(R-(E)) C23H25N3O2 (R-(E))-1-(1-Oxo-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-2-propenyl)-2-piperidineethanol FK 453 (+)-(R)-((E)-3-(2-Phenylpyrazolo(1,5-a)pyridin-3-yl)acryloyl)-2-piperidineethanol

Density	1.21g/cm3
Molecular Formula	C₂₃H₂₅N₃O₂
Molecular Weight	375.46400
Exact Mass	375.19500
PSA	57.84000
LogP	3.71590
Index of Refraction	1.636

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM9475500

CHEMICAL NAME :: 2-Piperidineethanol, 1-(1-oxo-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-2-pr openyl)-, (R-(E))-

CAS REGISTRY NUMBER :: 121524-18-3

LAST UPDATED :: 199606

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C23-H25-N3-O2

MOLECULAR WEIGHT :: 375.51

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 46,185,1996