Name | Ropivacaine-d7 Hydrochloride |
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Synonyms | (2S)-N-(2,6-dimethylphenyl)-1-(1,1,2,2,3,3,3-heptadeuteriopropyl)piperidine-2-carboxamide,hydrochloride |
Description | Ropivacaine-d7 hydrochloride is a deuterium labeled Ropivacaine (hydrochloride) (HY-B0563B)[1]. Ropivacaine hydrochloride is a potent?sodium channel?blocker and blocks impulse conduction via reversible inhibition of?sodium ion influx?in nerve fibrese[2][3]. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane[4]. Ropivacaine is widely used for neuropathic pain?management in vivo[2]. |
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Related Catalog | |
References |
Molecular Formula | C17H20D7ClN2O |
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Molecular Weight | 317.91 |
Exact Mass | 317.22500 |
PSA | 35.83000 |
LogP | 4.89580 |