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219138-02-0

219138-02-0 structure
219138-02-0 structure

Name Z-Ile-Glu-Thr-Asp 7-amido-4-trifluoromethylcoumarin
Synonyms MFCD01318832
(4S)-5-[[(2S,3R)-1-[[(2S)-3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-[[(2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-5-oxopentanoic acid
Cbz-IETD-AFC
Z-Ile-Glu-Thr-Asp-AFC
Z-IETD-AFC
Description Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity[1].
Related Catalog
References

[1]. Boudard D, et al. Increased caspase-3 activity in refractory anemias: lack of evidence for Fas pathway implication. Leukemia. 2002;16(11):2343-2345.

Molecular Formula C37H42F3N5O13
Molecular Weight 821.75000
Exact Mass 821.27300
PSA 279.77000
LogP 3.90270
Storage condition −20°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3